Why we may “never-ever” understand the seriousness of NSVT in HOCM ?
Hypertrophic cardiomyopathy (HCM) is the most common primary cardiac muscle disorder.It is one of the extensively studied medical entity in terms of pathology, genetics, electrophysiology and treatment.Though it has dramatic myocardial phenotypic expression , longevity can be near normal except in a minority who are prone for LV dysfunction and SCD due to the indirect electrical instability.These arrhythmia arise due to myocardial disarray , micro vascular disease or fibrosis.
NSVT by definition is runs of VT at a rate of > 100 /mt occurring less than 30 seconds.
How common is NSVT in HCM ?
On Holter study with 178 patients with HOCM (Adabag JACC 2005 ) 90 % showed VPDs
12% > 500 VPDs/24 h
40% had couplets,
30% had non-sustained ventricular tachycardia (NSVT).
Over a follow-up of 5.5 6% patients died suddenly (annual mortality rate, 1.1%)
For sudden death, NSVT on Holter ECG had negative and positive predictive values of 95% and 9%, and sensitivity and specificity of 45% and 69%, respectively.
In this series from StGeorge hospital London from 630 patient incidence of NSVT was 19% and 4 episodes were observed in 48 hr in most .Monserrat L, JACC 2003
What is the duration , How fast and how frequent is the NSVT ?
It is expected the total burden of NSVT would have a definite impact on outcome. Curiously the duration, fastness and frequency of NSVT was not related to prognosis in atleast one study (Monserrat L, JACC 2003)
Relationship bet...
Source: Dr.S.Venkatesan MD - Category: Cardiology Authors: dr s venkatesan Tags: hocm hcm how to manage non sustained vt in hcm hoc hypertrophic cardiomyopathy icd for nsvt managment issues in hocm nsvt in hocm sustained vs nonsustained vt in hocm Source Type: blogs
More News: Anxiety | Arrhythmia | Beta-Blockers | Cardiology | Cardiomyopathy | Cardiovascular | Electrocardiogram | Genetics | Heart | Heart Cancer | Hospital Management | Hospitals | Hypertrophic Cardiomyopathy | Hypertrophic Obstructive Cardiomyopathy | Pathology | Science | Study | Ventricular Arrhythmia | Ventricular Tachycardia