Risk factors for cardiovascular events of antidementia drugs in Alzheimer's disease patients

Conclusion The results of this study can help clinicians identify AD patients with a higher risk of cardiovascular events who therefore should be prescribed antidementia drugs cautiously.
Source: Journal of Clinical Gerontology and Geriatrics - Category: Geriatrics Source Type: research

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CONCLUSION: All these results indicate that SQC is an effective preventive and protective drug on skeletal muscle of diabetic macrovasculopathy, and could alleviate skeletal muscle tissue damage through affecting biological functions related to cell death and cell adhesion. PMID: 32096754 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research
Front cover:Mature neurons in the healthy central nervous system are considered to be permanently post ‐mitotic cells. In several neurodegenerative diseases, however, ectopic neuronal cell cycle events are found associated with regions of neuronal death. In the paper by Zhu et al., the authors use abnormal neuronal cell cycle activity as a screen to test natural compounds derived from marine bacter ia for their potential in preventing it and thus acting as neuroprotective agents.Image content: This image shows cerebellar Purkinje cells in one ‐month old mouse model of ataxia‐telangiectasia, a neurodegenerative diseas...
Source: Journal of Neurochemistry - Category: Neuroscience Tags: Issue Cover Source Type: research
We report the case of a 6-year-old child with anomalous origin of right coronary artery from aortic left coronary sinus, who underwent elective surgical replacement of stenotic and calcified conduit between the right ventricle and the main pulmonary artery. The surgery was complicated by acute myocardial infarction secondary to coronary extrinsic compression. The patient was successfully treated with urgent percutaneous coronary intervention (simultaneous V-stenting) and cangrelor infusion, subsequently switched to clopidogrel therapy. PMID: 32090666 [PubMed - as supplied by publisher]
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
In conclusion, chronic supplementation with 1% glycine did not have any significant detrimental side effects in our model. However, more studies are still necessary to evaluate the effect of 1% glycine supplementation in humans. PMID: 32091321 [PubMed - as supplied by publisher]
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
Authors: Osei-Owusu J, Yang J, Del Carmen Vitery M, Tian M, Qiu Z Abstract Severe local acidosis causes tissue damage and pain, and is associated with many diseases, including cerebral and cardiac ischemia, cancer, infection, and inflammation. However, the molecular mechanisms of the cellular response to extracellular acidic environment are not fully understood. We recently identified a novel and evolutionarily conserved membrane protein, PAC (also known as PACC1 or TMEM206), encoding the proton-activated chloride (Cl-) channel, whose activity is widely observed in human cell lines. We demonstrated that genetic del...
Source: Channels - Category: Molecular Biology Tags: Channels (Austin) Source Type: research
Changes in labeling, formularies, and drug formulations were among the factors contributing to shifts in type 2 diabetes drug prescribing practices in the US.Medscape Medical News
Source: Medscape Transplantation Headlines - Category: Transplant Surgery Tags: Diabetes & Endocrinology News Source Type: news
The $2.5 million project was among several okayed by the state Department of Health that will expand access to care in the region.
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Publication date: May 2020Source: Biomedical Signal Processing and Control, Volume 59Author(s): B. Richhariya, M. Tanveer, A.H. Rashid, for the Alzheimer’s Disease Neuroimaging Initiative
Source: Biomedical Signal Processing and Control - Category: Biomedical Science Source Type: research
CONCLUSION: Albumin values were not associated with wound complications or need for reoperation in patients undergoing body contouring. Further research is warranted. PMID: 32097112 [PubMed - as supplied by publisher]
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
Okay, I'm not an epidemiologist or a virologist. But I do know something about those subjects, I'm a public health professor, and I am an expert in clinical communication and risk communication. So I'm going to offer some observations that I hope will help people keep this public health scare in proper perspective and maybe be of practical use.There are two important parameters we need to understand the risk caused by any communicable disease. I'm going to broadly say transmissibility, and the probability that exposure will lead to serious disease.We often see transmissibility represented as a single number, called R0 or &...
Source: Stayin' Alive - Category: American Health Source Type: blogs
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