Infertility treatments 'not linked' to developmental delays

ConclusionThis prospective cohort study aimed to assess whether use of and type of infertility treatment was associated with a child's development up to the age of 36 months. The study found no convincing evidence that infertility treatment had any impact on a child's development, which will come as a relief to parents who have undertaken treatment. However, while this type of observational study is good for looking at links between an exposure and an outcome over a period of time, it is not able to prove direct cause and effect and say for certain whether there is any link between two factors. For example, various socioeconomic, health and lifestyle factors may be associated both with the chance of a couple experiencing fertility problems, and with the chance of their child experiencing developmental problems. Also, unlike in the UK, infertility treatment is rarely free in the US, which accentuates potential socioeconomic factors – it is less likely that poorer couples could afford treatment. The researchers have attempted to adjust their analyses for various factors that could be confounding the relationship, but it is not known whether these will have been able to account for the influence of all of them.Other limitations of the study include potential inaccuracies in completing the questionnaires, and missing data – though the researchers have used statistical modelling to account for gaps in the questionnaires.The study has many strengths, including that it u...
Source: NHS News Feed - Category: Consumer Health News Tags: Medical practice Pregnancy/child Source Type: news

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AbstractSTUDY QUESTIONDoes the provision of fertility (compared to control) information affect fertility-related knowledge, perceived threat of infertility, anxiety, physical stress and fertility plans in adolescents and emerging adults?SUMMARY ANSWERThe provision of fertility information was associated with increased fertility knowledge (emerging adults) and greater infertility threat (adolescents and emerging adults).WHAT IS KNOWN ALREADYAccording to fertility education research, adolescents and emerging adults know less than they should know about fertility topics. Fertility knowledge can be improved through the provisi...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
PDF Version (233 KB) About This Article Received: 1 September 2017 Accepted: 9 September 2017 Published: 1 November 2017 Address correspondence to C. Carignan, Department of Environmental Health, Building 1, 14th Floor, 665 Huntington Avenue, Boston, MA 02115 USA. Phone: (617) 432-4572. Email: carignan@hsph.harvard.edu Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and Supplemental Material published in EHP articles may not conform to 508 standards due to the complexity of the information being presented. If...
Source: EHP Research - Category: Environmental Health Authors: Tags: Erratum Source Type: research
Conclusions: Concentrations of MnBP, MBzP and MEHP similar to those found in the urine of pregnant women consistently altered hCG and PPARγ expression in primary placental cells. These findings provide evidence for the molecular basis by which phthalates may alter placental function, and they provide a preliminary mechanistic hypothesis for opposite responses by sex. https://doi.org/10.1289/EHP1539 Received: 23 December 2016 Revised: 6 September 2017 Accepted: 18 September 2017 Published: 31 October 2017 Address correspondence to J.J. Adibi, 130 Desoto Street, Parran Hall 5132, Pittsburgh, PA 15261 USA. Telephone...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
This report presents baseline estimates of the use of these preventive services before the publication of QFP that can be used to monitor progress toward improving the quality of preventive care received by women and men of reproductive age. PERIOD COVERED: 2011-2013. DESCRIPTION OF THE SYSTEM: Three surveillance systems were used to document receipt of preventive health services among women and men of reproductive age as recommended in QFP. The National Survey of Family Growth (NSFG) collects data on factors that influence reproductive health in the United States since 1973, with a focus on fertility, sexual act...
Source: MMWR Surveill Summ - Category: Epidemiology Authors: Tags: MMWR Surveill Summ Source Type: research
Conclusion: We think that exposures to hazardous substances migrating from FCAs require more attention. We recommend a) limiting the number and types of chemicals authorized for manufacture and b) developing novel approaches for assessing the safety of chemicals in FCAs, including unidentified chemicals that form during or after production. https://doi.org/10.1289/EHP644 Received: 10 June 2016 Revised: 08 June 2017 Accepted: 09 June 2017 Published: 11 September 2017 Address correspondence to J. Muncke, Food Packaging Forum, Staffelstrasse 8, 8045 Zurich, Switzerland. Telephone: 41-44-5155255. Email: jane.muncke@fp-fo...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
Conclusions: Using IVF to investigate human reproduction and pregnancy outcomes, we found that concentrations of some urinary PFR metabolites were negatively associated with proportions of successful fertilization, implantation, clinical pregnancy, and live birth. https://doi.org/10.1289/EHP1021 Received: 26 August 2016 Revised: 10 April 2017 Accepted: 02 June 2017 Published: 25 August 2017 Address correspondence to C. Carignan, Department of Environmental Health, Building 1, 14th Floor, 665 Huntington Avenue, Boston, MA 02115 USA. Phone: (617) 432-4572. Email: carignan@hsph.harvard.edu Supplemental Material is avail...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
Conclusion: These data indicate that TBBPA, triclosan, and BPA interact in vivo, consistent with evidence that TBBPA and triclosan inhibit enzymes that are critical for BPA and E2 metabolism. https://doi.org/10.1289/EHP1329 Received: 04 November 2016 Revised: 11 April 2017 Accepted: 13 April 2017 Published: 21 August 2017 Address correspondence to D. deCatanzaro, Dept. of Psychology, Neuroscience &Behaviour, McMaster University, 1280 Main St. West, Hamilton ON L8S 4K1, Canada. Telephone: (905) 525-9140, ext. 23014. Email: decatanz@mcmaster.ca Supplemental Material is available online (https://doi.org/10.1289/EHP1...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
AbstractSTUDY QUESTIONCan a consensus and evidence-driven set of terms and definitions be generated to be used globally in order to ensure consistency when reporting on infertility issues and fertility care interventions, as well as to harmonize communication among the medical and scientific communities, policy-makers, and lay public including individuals and couples experiencing fertility problems?SUMMARY ANSWERA set of 283 consensus-based and evidence-driven terminologies used in infertility and fertility care has been generated through an inclusive consensus-based process with multiple stakeholders.WHAT IS KNOWN ALREADY...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research
Conclusions: These results suggest that there is a seasonal driver for PE, with effects that are not modified by parity, latitude, fetal sex, or smoking. https://doi.org/10.1289/EHP963 Received: 14 August 2016 Revised: 24 January 2017 Accepted: 25 January 2017 Published: 29 June 2017 Address correspondence to C.R. Weinberg, Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 USA. Telephone: (919) 541-4927. Email: weinber2@niehs.nih.gov Supplemental Material is available online (https://doi.org/10.1289/EHP963). The authors declare they h...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
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