Urine-derived stem cells predict patient response to cholesterol-lowering drugs

High blood cholesterol is linked to an increased risk of heart disease and stroke. To identify new strategies to combat high cholesterol in genetically predisposed individuals, new preclinical models that mimic the underlying pathophysiology are needed. Researchers have now shown that cells derived from patient urine samples can be reprogrammed to rapidly generate patient-specific models of hypercholesterolemia. These models provide a tool to accurately predict patient response to cholesterol-lowering drugs.
Source: ScienceDaily Headlines - Category: Science Source Type: news