Cross-Talk in the Female Rat Mammary Gland: Influence of Aryl Hydrocarbon Receptor on Estrogen Receptor Signaling

Conclusion: Our data show transcriptome wide anti-estrogenic properties of ligand-activated AHR on ER-mediated processes in the mammary gland, thereby contributing to evaluate the chemopreventive and endocrine disrupting potential of AHR-ligands.

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Citation: Helle J, Bader MI, Keiler AM, Zierau O, Vollmer G, Chittur SV, Tenniswood M, Kretzschmar G. Cross-Talk in the Female Rat Mammary Gland: Influence of Aryl Hydrocarbon Receptor on Estrogen Receptor Signaling. Environ Health Perspect; http://dx.doi.org/10.1289/ehp.1509680.
Received: 6 January 2015
Accepted: 10 September 2015
Advance Publication: 15 September 2015
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Source: EHP Research - September 15, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research