Risk Factors for Attention and Behavioral Issues in Pediatric Sickle Cell Disease

This study was a retrospective chart review involving the outpatient records of 2 medical centers, Kennedy Krieger Institute and Johns Hopkins Hospital. Participants in the study included 59 children with sickle cell disease with a documented neurodevelopmental diagnosis, specifically attention deficit hyperactivity disorder, attention issues, behavioral issues, executive dysfunction, specific learning disabilities in math, reading, and reading comprehension, intellectual disabilities, developmental delay, fine motor disorders, language disorders, or autism spectrum disorders. Results. Children with sickle cell disease type hemoglobin S-β thalassemia plus had significantly higher odds of attention issues than children with sickle cell disease type hemoglobin SS (OR = 17.0, 95% CI = 1.99-145.00, P
Source: Clinical Pediatrics - Category: Pediatrics Authors: Tags: Articles Source Type: research

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CONCLUSION: We believe this program offers a solution to a component of this growing problem, and other clinical sites would benefit from such a program. Next steps include analysis and publication of results of implementation, including patient outcomes, engagement in treatment, and satisfaction. PMID: 32240081 [PubMed - as supplied by publisher]
Source: The Permanente journal - Category: General Medicine Tags: Perm J Source Type: research
Publication date: June 2020Source: Research in Developmental Disabilities, Volume 101Author(s): Benjamin A. Kennert, Timothy S. Harshorne, Sandra Kanouse, Carl Johnson
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Publication date: May 2020Source: Research in Developmental Disabilities, Volume 100Author(s):
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
COVID-19 can cause a pneumonia-like lung infection, with a range of symptoms from mild or absent in some to life-threatening in others.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Video clip features Ali Asgari, who can control a remote control plane with his toes and play music with his hands at the same time
Source: Disabled World - Category: Disability Tags: Hobbies Source Type: news
CONCLUSION: This case highlights the utility of LT as a viable treatment option for acute sickle cell intrahepatic cholestasis. PMID: 32231764 [PubMed]
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
Authors: Duruel O, Erduran NE, Tözüm TF Abstract Exposure of maxillary gingiva more than 3 mm while smiling is referred to as "excessive gingival display" or "gummy smile." Various treatment options for excessive gingival display are published in the literature, including lip repositioning, crown lengthening, botulinum toxin-A injections, and orthognathic surgeries. This case report aims to present a novel approach to the lip-repositioning procedure for treatment of excessive gingival display. The patient, who visited the department to demand a more esthetic smile, was diagnosed with e...
Source: International Journal of Periodontics and Restorative Dentistry - Category: Dentistry Tags: Int J Periodontics Restorative Dent Source Type: research
FRIDAY, April 3, 2020 -- People with asthma and other lung diseases are at increased risk for serious complications from COVID-19, caution experts from the American Lung Association. " Everyone's health is at risk from COVID-19, and those living with...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Gun-related injuries are a hotly debated sociopolitical topic in the United States. Annually, more than 33 million Americans seek heathcare services for mental health issues. These conditions are the leading cause of combined disability and death among wom...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news
Purpose of review The current review focuses on recent insights into the development of small molecule therapeutics to treat the β-globinopathies. Recent findings Recent studies of fetal γ-globin gene regulation reveal multiple insights into how γ-globin gene reactivation may lead to novel treatment for β-globinopathies. Summary We summarize current information regarding the binding of transcription factors that appear to be impeded or augmented by different hereditary persistence of fetal hemoglobin (HPFH) mutations. As transcription factors have historically proven to be difficult to target ...
Source: Current Opinion in Hematology - Category: Hematology Tags: ERYTHROID SYSTEM AND ITS DISEASES: Edited by Narla Mohandas and Sandrina Kinet Source Type: research
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