Significance, definition, classification and risk factors of chronic kidney disease in South Africa.

The objective of diagnosing CKD lies in its future prevention, earlydetection and proper treatment, which will prevent or delay functional deterioration.Primary hypertension (PH) occurs in 25% of South Africa (SA)'s black population and is the putative cause of stage 5 CKD in 40 - 60%of these patients. Moreover, in this group, stage 5 CKD occurs at a relatively young age (35 - 45 years) compared with other populationgroups in whom stage 5 CKD resulting from PH usually occurs between 60 and 70 years of age. In the cohort study, PH has been found in12 - 16% of black school learners (mean age 17 years) compared with 1.8 - 2% of other ethnic groups (mixed race, Asian, white). End-stagerenal failure (ESRF) is the fifth most common cause of death in SA, excluding post-traumatic cases. In addition, undiagnosed or poorlycontrolled PH is a potent risk factor for other cardiovascular disease (CVD), e.g. congestive cardiac failure, myocardial infarction, stroke.Significant protein is also associated with CVD and protein >1 g/d is a significant risk factor for ESRF. PMID: 26294833 [PubMed - as supplied by publisher]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research