In-silico Studies, Design, and Synthesis of Pyrimidine-linked Benzothiazoles for its Anticonvulsant Potential
CONCLUSION: Thus, the compounds BPD-15 and BPD-5 have shown a considerable affinity towards the sodium channel as compared to the standard drug Riluzole. Compound BPD-14 showed good drug compatibility, and compounds BPD-1, BPD-2, BPD-11, BPD-12, BPD-13, BPD-14, BPD-15 showed good ADME values.PMID:38715333 | DOI:10.2174/0115701638299019240418055933
Source: Current Drug Discovery Technologies - Category: Drugs & Pharmacology Authors: Amol Kale Rajendra Kakde Smita Pawar Rutuja Thombare Dhanashree Zope Ishwar Kakde Source Type: research
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