Algorithm for detection and screening of familial hypercholesterolemia in Lithuanian population

CONCLUSIONS: Most patients in this study were classified as probable or possible FH without difference of age and sex. The median age of FH diagnosis was 47 years with significantly older females than males, which refers to the strong interface of this study with the LitHir programme. CAD and premature CAD were more common among patients with probable and definite FH, as well as those with an FH-causing mutation. The algorithm described in this study is the first attempt in Lithuania to implement a specific tool which allows to maximise FH detection rates, establish an accurate diagnosis of FH, excluding secondary causes of dyslipidaemia, and to select patients for cascade screening initiation more precisely.PMID:38715054 | DOI:10.1186/s12944-024-02124-x

Source: Atherosclerosis - May 7, 2024 Category: Cardiology Authors: Urte Aliosaitiene Zaneta Petrulioniene Egidija Rinkuniene Antanas Mainelis Egle Brazdziuniene Urte Smailyte Vaida Sileikiene Aleksandras Laucevicius Source Type: research