Terf2ip deficiency accelerates non-alcoholic steatohepatitis through regulating lipophagy and fatty acid oxidation via Sirt1/AMPK pathway
CONCLUSIONS: These results revealed that Terf2ip played a protective role in the progression of NASH through regulating lipophagy and FAO by binding to Sirt1 promoter. Our findings provided a potential therapeutic target for the treatment of NASH.PMID:38697492 | DOI:10.1016/j.freeradbiomed.2024.04.238
Source: Free Radical Biology and Medicine - Category: Biology Authors: Yirui Wang Shuochen Liu Ming Ni Yananlan Chen Ruixiang Chen Jifei Wang Wangjie Jiang Tao Zhou Shilong Fan Jiang Chang Xiao Xu Yaodong Zhang Yue Yu Xiangcheng Li Changxian Li Source Type: research
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