Disproportionate neuroanatomical effects of < em > DCC < /em > haploinsufficiency in adolescence compared with adulthood: links to dopamine, connectivity, covariance, and gene expression brain maps in mice

CONCLUSION: The neuroanatomical phenotype of DCC haploinsufficiency described in mice parallels that observed in DCC-haploinsufficient humans. It is critical to understand the DCC-haploinsufficient mouse as a clinically relevant model system.PMID:38692693 | DOI:10.1503/jpn.230106

Source: J Psychiatry Neurosc... - May 1, 2024 Category: Psychiatry Authors: Daniel Hoops Yohan Yee Christopher Hammill Sammi Wong Colleen Manitt Barry J Bedell Lindsay Cahill Jason P Lerch Cecilia Flores John G Sled Source Type: research