Targeted Knockdown of Hepatic delta-5 Fatty Acid Desaturase FADS1 Aggravates Atherosclerosis in ApoE(-/-) Mice

CONCLUSIONS: Our study demonstrated that knockdown of hepatic Fads1 in ApoE-⁣/- mice aggravates spontaneous atherosclerosis and NAFLD but does not affect peripheral atherosclerosis (femoral artery) induced by vascular cuff combined with tandem stenosis.PMID:38682200 | DOI:10.31083/j.fbl2904131

Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Qiulei Liu Peng Wang Zhao Yang Yue Dai Sheng Wang Source Type: research