The LEPIS-HuR-TMOD4 axis regulates hepatic cholesterol homeostasis and accelerates atherosclerosis

CONCLUSIONS: These results suggest that the LEPIS-HuR-TMOD4 axis is a potential intervention target for dysregulated hepatic cholesterol homeostasis and AS and may provide the basis for further reductions in the circulating LDL-C concentration and arterial plaque burden.PMID:38663275 | DOI:10.1016/j.atherosclerosis.2024.117554

Source: Atherosclerosis - April 25, 2024 Category: Cardiology Authors: Ping LYu Hangyu Pan Kexin Hu Yazhi Xue Qinxian Li Rongzhan Lin Shaoyi Zheng Zhigang Guo Kai Guo Source Type: research