Exploring the role of coagulation-related genes in renal cell carcinoma: Implications for tumor microenvironment and prognostic biomarkers

CONCLUSION: There is an obvious correlation between the coagulation and the tumor microenvironment in ccRCC. As a key coagulation-related gene, MMP9 may promote the progression of renal cell carcinoma by influencing immune infiltration of CD8+T cells and Treg cells. Additionally, the risk score could be used as a durable prognostic biomarker, which could assist in clinical decision making for ccRCC patients.PMID:38663187 | DOI:10.1016/j.compbiolchem.2024.108082

Source: Computational Biology and Chemistry - April 25, 2024 Category: Bioinformatics Authors: Yang Qiu Yuanpeng Liao Jianqiang Zhang Yuedian Ye Zhongshu Zhang Zheng Jiang Jiaai Zhang Jinghan Xin Shidong Lv Hongmei Peng Source Type: research