Conditioned medium-enriched umbilical cord mesenchymal stem cells: a potential therapeutic strategy for spinal cord injury, unveiling transcriptomic and secretomic insights

CONCLUSIONS: In conclusion, the CBG-UCNSC method effectively preserved the integrity of the transplanted neuronal-like cells and improved locomotor function. Thus, CM-enriched cells can potentially reduce biosafety risks associated with animal content, making them a promising option for clinical applications in treating spinal cord injuries.PMID:38658405 | DOI:10.1007/s11033-024-09503-8

Source: Mol Biol Cell - April 24, 2024 Category: Molecular Biology Authors: Rajasekaran Subbarayan Dinesh Murugan Girija Selvaraj Thirupathi Kumara Raja Alagudurai Krishnamoorthy Dhasarathdev Srinivasan Rupendra Shrestha Nityanand Srivastava Suresh Ranga Rao Source Type: research