Simple modeling of familial Alzheimer's disease using human pluripotent stem cell-derived cerebral organoid technology

CONCLUSION: Our model effectively recapitulates AD pathology. Hence, it is a valuable platform for understanding the mechanisms underlying AD pathogenesis and can be used to test the efficacy of anti-AD drugs.PMID:38659053 | DOI:10.1186/s13287-024-03732-1

Source: Cell Research - April 24, 2024 Category: Cytology Authors: Mu Seog Choe Han Cheol Yeo Joong Sun Kim Jean Lee Hae Jun Lee Hyung-Ryong Kim Kyung Min Baek Na-Yeon Jung Murim Choi Min Young Lee Source Type: research