The effectiveness of parenteral agents for pain reduction in patients with migraine presenting to emergency settings: A  systematic review and network analysis

CONCLUSIONS: Various parenteral agents were found to provide effective pain relief. Considering the consistent improvements across various outcomes, combination therapy, as well as monotherapy of either metoclopramide or neuroleptics are recommended as first-line options for managing acute migraine pain. There are risks of adverse events, especially akathisia, following treatment with these agents. We recommend that a shared decision-making model be considered to effectively identify the best treatment option based on the patient's needs.PMID:38644702 | DOI:10.1111/head.14704

Source: Headache - April 22, 2024 Category: Neurology Authors: Scott W Kirkland Lloyd Visser Jillian Meyer Daniela R Junqueira Sandra Campbell Cristina Villa-Roel Benjamin W Friedman Nana Owusu Essel Brian H Rowe Source Type: research