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Metoclopramide Injection, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 24, 2017 Category: Drugs & Pharmacology Source Type: news

Metoclopramide Injection, USP (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - October 23, 2017 Category: Drugs & Pharmacology Source Type: news

2016 Updated MASCC/ESMO consensus recommendations: Management of nausea and vomiting in advanced cancer
The aim of this paper was to develop a set of evidence-based guidelines for the management of different syndromes related to nausea and vomiting in advanced cancer. The authors found that the level of evidence in most studies is low, but conclude that the drug of choice is metoclopramide, with alternative options including haloperidol, levomepromazine, or olanzapine. For bowel obstruction, the recommendation is to use octreotide given alongside an antiemetic (haloperidol) and where octreotide is not an option to use an anticholinergic antisecretory agent. For opioid-induced nausea and vomiting, no recommendation could be m...
Source: Current Awareness Service for Health (CASH) - April 25, 2017 Category: Consumer Health News Source Type: news

Metoclopramide may be effective for clozapine-induced hypersalivation
Clozapine-induced hypersalivation is the most prevalent adverse effect experienced by patients treated with clozapine and negatively impacts on quality of life,1 with symptoms particularly prevalent at night-time. Pharmacotherapeutic strategies employed to date, based on multiple mechanisms including antimuscarinic agents and α-2 agonists have largely been associated with, at most, a minimal therapeutic effect.2 The development of strategies would thus be welcomed given the lack of effective treatment options, with such strategies hopefully being associated with an improvement in clinical outcome and perhaps also lon...
Source: Current Awareness Service for Health (CASH) - March 27, 2017 Category: Consumer Health News Source Type: news

Looking for relief, pregnant women turn to marijuana despite medical advice
According to data from the Centers for Disease Control and Prevention ’s National Vital Statistics Reports, more than one in five U.S. births now occur in states where marijuana is legal. That ’s triggered a concern among health professionals about the use of marijuana by pregnant women.Along with the broader availability of marijuana comes the perception that it is a harmless substance, health professionals say. But pregnant women, who may be seeking relief from a variety of ailments, should be aware of the potential health consequences of marijuana use.To understand how marijuana affects expectant mother...
Source: UCLA Newsroom: Health Sciences - March 2, 2017 Category: Universities & Medical Training Source Type: news

Reglan Injection (Metoclopramide Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 30, 2016 Category: Drugs & Pharmacology Source Type: news

Metozolv ODT (Metoclopramide Hydrochloride Orally Disintegrating Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 30, 2016 Category: Drugs & Pharmacology Source Type: news

Reglan ODT (Metoclopramide Orally Disintegrating Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - November 30, 2016 Category: Drugs & Pharmacology Source Type: news

Reglan (Metoclopramide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 8, 2016 Category: Drugs & Pharmacology Source Type: news

Treatment in carbon monoxide poisoning patients with headache: a prospective, multicenter, double-blind, controlled clinical trial - Ocak T, Tekin E, Basturk M, Duran A, Serinken M, Emet M.
BACKGROUND: There is a lack of specificity of the analgesic agents used to treat headache and underlying acute carbon monoxide poisoning. OBJECTIVE: To compare effectiveness of "oxygen alone" vs "metoclopramide plus oxygen" vs "metamizole plus oxyg... (Source: SafetyLit)
Source: SafetyLit - August 26, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Metoclopramide, Ibuprofen May Be Alternatives to Acetazolamide for Altitude Sickness Metoclopramide, Ibuprofen May Be Alternatives to Acetazolamide for Altitude Sickness
The antiemetic drug metoclopramide may reduce symptoms of acute mountain sickness (AMS) and serve as an alternative for those who cannot take the common first-line treatment acetazolamide, a new study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 8, 2016 Category: Consumer Health News Tags: Emergency Medicine News Source Type: news

Fentanyl can cause serotonin syndrome
3.5 out of 5 stars Serotonin Syndrome Induced by Fentanyl in a Child: Case Report. Robles LA. Clin Neuropharmacol 2015 Sept-Oct;38:206-8. Abstract When many clinicians think of serotonin syndrome (SS), they consider the usual suspects: Selective Serotonin Uptake Inhibitors (SSRIs) Citalopram Fluoxetine Sertraline Escitalopram Paroxetine Serotonin-Norepinephrine Reuptake Inhibitors Venlafaxine Duloxetine Antidepressants Trazodone Buspirone Clomipramine Aside from these common culprits, there are other commonly used drugs whose clear association with serotonin syndrome is less-often realized: Fentanyl ...
Source: The Poison Review - July 8, 2016 Category: Toxicology Authors: Leon Gussow Tags: Medical fentanyl opioid serotonin syndrome Source Type: news

New AHS Consensus on Emergency Migraine ManagementNew AHS Consensus on Emergency Migraine Management
Intravenous metoclopramide and prochlorperazine, and subcutaneous sumatriptan, get the highest level of recommendation from a panel on acute treatment of migraine in the emergency department Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 17, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Metoclopramide and Diphenhydramine Blunt Pregnancy HeadachesMetoclopramide and Diphenhydramine Blunt Pregnancy Headaches
The two-drug combination is more expensive than codeine for reducing headaches in pregnant women, but is more effective and worth the cost, say researchers. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 15, 2015 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

How Long Before Gastroparesis Improves?
Discussion “[Gastroparesis] (GP) is a motor and sensory disorder of the stomach characterized by delayed gastric emptying in the absence of mechanical obstruction. Symptoms classically include nausea, vomiting, early satiety, bloating, postprandial fullness, abdominal pain and weight loss….GP is often not recognized and thus can remain untreated in children.” In the adult population, the age adjusted prevalence of GP is 9.6 (for men) and 37.8 (for women) per 100,000. There is no specific prevalence data available for children. It appears from some data that GP identification is rising and some data sugge...
Source: PediatricEducation.org - February 24, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Popular Morning Sickness Drug Safe in Pregnancy, Study Finds
Women taking metoclopramide can be reassured by the findings, expert says (Source: WebMD Health)
Source: WebMD Health - October 15, 2013 Category: Consumer Health News Source Type: news

Metoclopramide: No Link Seen With Birth Defects, Stillbirth Metoclopramide: No Link Seen With Birth Defects, Stillbirth
A study of more than 40,000 women who used metoclopramide during pregnancy found no significant link between use of the drug and risks for congenital malformations or other adverse outcomes. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 15, 2013 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Nausea Drug Safe During Pregnancy (CME/CE)
(MedPage Today) -- There was no association between exposure to metoclopramide (Reglan) during pregnancy and an increased risk of birth defects, spontaneous abortion, or stillbirth, according to results of a large, register-based study. (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - October 15, 2013 Category: OBGYN Source Type: news

Medication taken for nausea during pregnancy not associated with increased risk of major malformations, stillbirth
In an analysis that included more than 40,000 women exposed to the nausea medication metoclopramide in pregnancy, use of this drug was not associated with significantly increased risk of major congenital malformations overall, spontaneous abortion, and stillbirth, according to a study in the October 16 issue of JAMA. More than 50 percent of pregnant women experience nausea and vomiting, typically early in their pregnancy. The care of most women is managed conservatively, but 10 percent to 15 percent of those with nausea and vomiting will eventually receive drug treatment... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 15, 2013 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news

Metoclopramide Injection And Ondansetron Injection by Hospira: Recall - Glass Strand Particulates Caused By Glass Supplier
Administration of an injectable with the presence of foreign particulates may result in local inflammation, thrombophlebitis, and/or low-level allergic response. (Source: FDA MedWatch)
Source: FDA MedWatch - October 2, 2013 Category: American Health Source Type: news

Hospira issues a voluntary nationwide recall of one lot of metoclopramide injection, usp, and two lots of ondansetron injection, usp, due to glass (glass strands) particulates caused by glass supplier defect
Hospira, Inc. (NYSE: HSP), announced today it initiated a voluntary nationwide recall of one lot of Metoclopramide Injection, USP, 10 mg/2 mL (5 mg/mL), NDC 0409-3414-01, Lot 28-104-DK and two lots of Ondansetron Injection, USP, 4 mg/2 mL, (2 mg/mL), NDC 0409-4755-03, Lots 29-484-DK and 29-510-DK. This action is due to a confirmed vial defect where glass particulate matter (glass strands) were identified as being affixed to the inside of the vial walls. There is potential for the glass particulates to dislodge into the solution. (Source: Food and Drug Administration)
Source: Food and Drug Administration - October 2, 2013 Category: Food Science Source Type: news

The Metoclopramide Black Box Warning for Tardive DyskinesiaThe Metoclopramide Black Box Warning for Tardive Dyskinesia
This study investigated the effect on one large practice. The American Journal of Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 15, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Clinical Notes: Nausea Drug Risky for Kids
(MedPage Today) -- Metoclopramide should be avoided whenever possible in children because of the drug's neurological toxicity, the European Medicines Agency said. Also this week: A new TB test won FDA approval. (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - July 28, 2013 Category: American Health Source Type: news

Europe Recommends Restrictions for MetoclopramideEurope Recommends Restrictions for Metoclopramide
The Committee on Medicinal Products for Human Use has recommended restrictions on metoclopramide to minimize neurologic adverse effects. News Alerts (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 26, 2013 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

Metoclopramide, Ondansetron Cut Nausea in Cesarean DeliveryMetoclopramide, Ondansetron Cut Nausea in Cesarean Delivery
A new study has suggested that adding metoclopramide and ondansetron drugs to a phenylephrine infusion during a cesarean delivery reduces vomiting and nausea. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 7, 2013 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news