Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation

In conclusion, we identify a novel feedback inhibition pathway where dietary DHA downregulates its liver synthesis by inhibiting EPA elongation.PMID:38649096 | DOI:10.1016/j.jlr.2024.100548

Source: Cell Research - April 22, 2024 Category: Cytology Authors: Adam H Metherel Rodrigo Valenzuela Brinley J Klievik Giulia Cisbani Ruxandra D Rotarescu Melissa Gonzalez-Soto C éline Cruciani-Guglielmacci Sophie Lay é Christophe Magnan David M Mutch Richard P Bazinet Source Type: research