Stepwise combined cell transplantation using mesenchymal stem cells and induced pluripotent stem cell-derived motor neuron progenitor cells in spinal cord injury

CONCLUSIONS: Our findings show that stepwise combined cell therapy can induce alterations in the microenvironment for effective cell therapy in SCI. The in vitro results suggest that co-culturing hMSC and iMN can synergistically promote induction of MN neurite outgrowth.PMID:38650015 | DOI:10.1186/s13287-024-03714-3

Source: Cell Research - April 22, 2024 Category: Cytology Authors: Jang-Woon Kim Juryun Kim Hyunkyung Mo Heeju Han Yeri Alice Rim Ji Hyeon Ju Source Type: research