Comparative effectiveness and safety of ticagrelor and clopidogrel in patients with or without chronic liver disease: a nationwide cohort study

Although the effectiveness and safety of ticagrelor versus clopidogrel may differ in patients with chronic liver disease, there is a scarcity of evidence comparing ticagrelor and clopidogrel in patients with chronic liver disease. We aimed to evaluate the risk of major adverse cardiovascular events (MACE) and major bleeding associated with ticagrelor versus clopidogrel in patients undergoing percutaneous coronary intervention (PCI) due to acute coronary syndrome by chronic liver disease status.

Source: The American Journal of Medicine - April 17, 2024 Category: General Medicine Authors: Bin Hong, Sungho Bea, Seng Chan You, Yoosoo Chang, Won Kim, Ju-Young Shin Tags: Clinical Research Study Source Type: research