Plant-Derived Natural Product Guggulipid Alleviates Trigeminal Neuropathic Pain in Mice

One type of chronic pain that is particularly traumatic for patients is trigeminal neuropathic pain, which is caused by inflammation and demyelination of the trigeminal nerve pathways. Commiphora mukul, is well known in the traditional Indian system of medicine, and has been used to treat ailments such as obesity, bone fractures, arthritis, inflammation, cardiovascular diseases, and lipid disorders. Here we investigated the effect of guggulipid, a neutral fraction of ethyl acetate extract of gum resin of the Commiphora mukul Engl.
Source: The Journal of Pain - Category: Materials Science Authors: Source Type: research