Transcriptional Changes in Dilated Cardiomyopathy After LVAD Treatment
Purpose: Dilated cardiomyopathy (DCM) is characterized by transcriptional changes. Clinical recovery after LVAD implant is highly variable and transcriptional changes often persist. Our goal was to identify micro-RNAs (miRNAs) associated with heart failure (HF) and to evaluate responses to LVAD therapy to better understand epigenetic mechanisms regulating differential gene expression (DGE).
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: , D. Liescheski, H. Basma, M. Urban, A. Burdorf, J. Um, B. Lowes Source Type: research
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