Substitution of dietary monounsaturated fatty acids from olive oil for saturated fatty acids from lard increases LDL apolipoprotein B-100 fractional catabolic rate in subjects with dyslipidemia associated with insulin resistance: a randomized controlled trial

CONCLUSIONS: This study demonstrated that substituting dietary MUFAs for SFAs decreases LDL-C levels and LDL PS by increasing LDL apoB-100 FCR and results in an overall improved plasma lipidomic profile in individuals with IR-induced lipidemia.TRIAL REGISTRATION: clinicaltrials.gov NCT03872349.PMID:38518848 | DOI:10.1016/j.ajcnut.2024.03.015

Source: Am J Clin Nutr - March 22, 2024 Category: Nutrition Authors: Louis-Charles Desjardins Francis Bri ère Andr é J Tremblay Maryka Rancourt-Bouchard Jean-Philippe Drouin-Chartier Jacques Corbeil Val éry Lemelin Am élie Charest Ernst J Schaefer Beno ît Lamarche Patrick Couture Source Type: research