Impact of CYP1A1 variants on the risk of acute lymphoblastic leukemia: evidence from an updated meta-analysis

CONCLUSION: Our comprehensive analysis indicates that the T3801 and A2455G polymorphisms of CYP1A1 may increase the risk of ALL depending on ethnicity. Therefore, both variants should be considered promising biomarkers for ALL risk. Further large-scale investigations are necessary to assess other factors, such as gene-gene or gene-environment interactions.PMID:38485870 | PMC:PMC10917727 | DOI:10.1007/s44313-024-00007-9

Source: Blood Research - March 15, 2024 Category: Hematology Authors: Imen Frikha Rim Frikha Moez Medhaffer Hanen Charfi Fatma Turki Moez Elloumi Source Type: research