Immuno-oncological effects of standard anticancer agents and commonly used concomitant drugs: an in vitro assessment

CONCLUSION: We utilized a miniaturized tumor-immune model to enable time and cost-effective evaluation of a broad panel of drugs in an immuno-oncology setting in vitro. Using this approach, immunomodulatory effects exerted by TKIs and statins were identified.PMID:38444002 | PMC:PMC10913607 | DOI:10.1186/s40360-024-00746-6

Source: BMC Pharmacology and Toxicology - March 5, 2024 Category: Drugs & Pharmacology Authors: Tove Selvin Malin Berglund Lena Lenhammar Magnus Lindskog Malin Jarvius Rolf Larsson Peter Nygren M årten Fryknäs Claes R Andersson Source Type: research