Obesity-induced downregulation of miR-192 exacerbates lipopolysaccharide-induced acute lung injury by promoting macrophage activation

CONCLUSIONS: Our study indicates that obesity-induced downregulation of miR-192 expression exacerbates LPS-induced ALI by promoting macrophage activation. Targeting macrophages and miR-192 may provide new therapeutic avenues for obesity-associated ALI.PMID:38486141 | PMC:PMC10938800 | DOI:10.1186/s11658-024-00558-w
Source: Cellular and Molecular Biology Letters - Category: Biochemistry Authors: Source Type: research