Obesity-induced downregulation of miR-192 exacerbates lipopolysaccharide-induced acute lung injury by promoting macrophage activation
CONCLUSIONS: Our study indicates that obesity-induced downregulation of miR-192 expression exacerbates LPS-induced ALI by promoting macrophage activation. Targeting macrophages and miR-192 may provide new therapeutic avenues for obesity-associated ALI.PMID:38486141 | PMC:PMC10938800 | DOI:10.1186/s11658-024-00558-w
Source: Cellular and Molecular Biology Letters - Category: Biochemistry Authors: Siqi Wu Wenjing Tang Ling Liu Ke Wei Yin Tang Jingyue Ma Hongbin Li Yichan Ao Source Type: research
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