Predictors of Treatment Failure in Young, Non-Smoking, Non-Drinking Patients with Squamous Cell Carcinoma of the Oral Tongue

A history of significant alcohol and tobacco use are known risk factors for the development of squamous cell carcinoma of the oral tongue (SCCOT). Despite a documented rise in disease incidence in young patients with no known risk factors, little is understood about the pathogenesis and clinical outcomes in this cohort. High rates of treatment failure in these patients, when compared to older patients with SCCOT and no risk factors, warrants further study. We aim to identify specific demographic, clinical, or pathological predictors of treatment failure in young, SCCOT patients with no prior drinking or smoking history.

Source: International Journal of Radiation Oncology * Biology * Physics - March 14, 2024 Category: Radiology Authors: N. Rodriguez, D.R. Dickstein, K. Sindhu, J.T. Liu, J. Barlow, S. Reed, W.H. Westra, D. Kirke, M.V. Gerwen, M. Posner, D.K. Misiukiewicz, S. Roof, E. Genden, R.L. Bakst Tags: 122 Source Type: research