Normothermic regional perfusion procurement for abdominal organ donors: techniques and troubleshooting

Curr Opin Organ Transplant. 2024 Mar 12. doi: 10.1097/MOT.0000000000001140. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Normothermic regional perfusion (NRP) is a novel procurement technique for donation after circulatory death (DCD) in the United States. It was pioneered by cardiothoracic surgery programs and is now being applied to abdominal-only organ donors by abdominal transplant programs. Multiple technical approaches can be used for abdominal-only NRP DCD donors and this review describes these techniques.RECENT FINDINGS: NRP has been associated with higher utilization of organs, particularly liver and heart grafts, from DCD donors and with better recipient outcomes. There are lower rates of delayed graft function in kidney transplant recipients and lower rates of ischemic cholangiopathy in liver transplant recipients. These benefits are driving increased interest from abdominal transplant programs in using NRP for DCD procurements.SUMMARY: This paper describes the technical aspects of NRP DCD that allow for maximization of its use based on different donor and policy characteristics.PMID:38465664 | DOI:10.1097/MOT.0000000000001140
Source: Current Opinion in Organ Transplantation - Category: Transplant Surgery Authors: Source Type: research