Pathologic complete response in patients with esophageal cancer receiving neoadjuvant chemotherapy or chemoradiation: A systematic review and meta ‐analysis

ConclusionsUnder one-third of patients with esophageal cancer who receive neoadjuvant chemo(radiation) experience pCR. Patients diagnosed with squamous cell carcinomas had higher rates of pCR than those with adenocarcinomas. As pCR represents an increasingly utilized endpoint in neoadjuvant trials, these estimates of pooled pCR rates may serve as an important benchmark for future trial design.

Source: Cancer Medicine - March 8, 2024 Category: Cancer & Oncology Authors: Charles E. Gaber, Jyotirmoy Sarker, Abdullah I. Abdelaziz, Ebere Okpara, Todd A. Lee, Samuel J. Klempner, Ryan D. Nipp Tags: RESEARCH ARTICLE Source Type: research