Hypoxia preconditioning of human amniotic mesenchymal stem cells enhances proliferation and migration and promotes their homing via the HGF/C-MET signaling axis to augment the repair of acute liver failure

CONCLUSIONS: Hypoxic preconditioning depicted no impact on the morphology and phenotype features of the human amniotic mesenchymal stem cells, but it can promote their proliferation, migration, anti-apoptotic effect, and homing rate and improve the repair of acute liver failure, which might be mediated by the HGF/c-Met signaling axis.PMID:38442547 | DOI:10.1016/j.tice.2024.102326

Source: Tissue and Cell - March 5, 2024 Category: Cytology Authors: Qian Wang Yuwen Li Hui Yuan Linya Peng Zixing Dai Ye Sun Rui Liu Wenting Li Jun Li Chuanlong Zhu Source Type: research