Mitochondrial ferritin alleviates ferroptosis in a kainic acid-induced mouse epilepsy model by regulating iron homeostasis: Involvement of nuclear factor erythroid 2-related factor 2
CONCLUSIONS: In epilepsy, Nrf2 modulates ferroptosis by involving the expression of FtMt and may be a potential therapeutic mechanism of neuronal injury after epilepsy. Targeting this relevant process for treatment may be a therapeutic strategy to prevent epilepsy.PMID:38439636 | DOI:10.1111/cns.14663
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: Yu Song Mengjiao Gao Boyang Wei Xiaowei Huang Zeyu Yang Junjie Zou Yanwu Guo Source Type: research
More News: Adenoviruses | Brain | Epilepsy | Genetics | Iron | Men | Mitochondria | Mitochondrial Disease | Neurology | Neuroscience