Enhanced polygenic risk score incorporating gene-environment interaction suggests the association of major depressive disorder with cardiac and lung function

CONCLUSIONS: Our findings underscore the profound impact of depression on cardiac and lung function, highlighting the enhanced efficacy of considering gene-environment interactions in PRS-based studies.PMID:38436562 | DOI:10.1093/bib/bbae070

Source: Briefings in Bioinformatics - March 4, 2024 Category: Bioinformatics Authors: Chuyu Pan Bolun Cheng Xiaoyue Qin Shiqiang Cheng Li Liu Xuena Yang Peilin Meng Na Zhang Dan He Qingqing Cai Wenming Wei Jingni Hui Yan Wen Yumeng Jia Huan Liu Feng Zhang Source Type: research