Network pharmacology analysis and clinical efficacy of the traditional Chinese medicine Bu-Shen-Jian-Pi. Part 3: Alleviation of hypoxia, muscle-wasting, and modulation of redox functions in amyotrophic lateral sclerosis
CONCLUSION: BSJP treatment reduced the rate of progression of amyotrophic lateral sclerosis according to the ALS-SSITS and ALSFRS scores and significantly reduced the rate of deterioration in muscle function in the limbs of amyotrophic lateral sclerosis patients. The modes of action of BSJP in treating amyotrophic lateral sclerosis are probably diverse and multi targeted, some of which may involve regulation of serum vitamin D3 and alleviation of the impairments in liver and kidney function.PMID:38431830 | DOI:10.5414/CP204520
Source: Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Authors: Rui Li Xiaojing Han Qiudong Wang Chenghui Wang Wei Jing Haihan Zhang Jun Wang Weidong Pan Source Type: research
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