BMSC-Exosomes attenuate ALP dysfunction by restoring lysosomal function via the mTOR/TFEB Axis to reduce cerebral ischemia-reperfusion injury

CONCLUSION: BMSC-Exos could attenuate ALP dysfunction by restoring lysosomal function after CIRI by inhibiting mTOR and then promoting TFEB nucleus translocation.PMID:38403042 | DOI:10.1016/j.expneurol.2024.114726

Source: Experimental Neurology - February 25, 2024 Category: Neurology Authors: Haining Liu Chen Li Xiaofeng Zhang Hui Chen Qi Zhang Yuting Zeng Shuqi Zheng Jihua Zou Yijin Zhao Xiaoyan Zheng Guozhi Huang Qing Zeng Source Type: research