Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti-PD-1 Immune Checkpoint Inhibitor Cancer Therapy

This study sheds light on underlying immunological mechanisms in ICI myocarditis and provides the basis for further detailed analyses of diagnostic and therapeutic strategies.PMID:38426910 | DOI:10.4049/jimmunol.2300841

Source: Journal of Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Jeremy J Racine John F Bachman Ji-Gang Zhang Adel Misherghi Raheem Khadour Sana Kaisar Olivia Bedard Catherine Jenkins Annie Abbott Elvira Forte Peter Rainer Nadia Rosenthal Susanne Sattler David V Serreze Source Type: research