Evaluating CD4 and Foxp3 mRNA Expression in Tissue Specimens of Celiac Disease and Colorectal Cancer Patients

CONCLUSION: This study reveals differential expression patterns of CD4 and Foxp3 mRNA in CRC and CD patients. Upregulated CD4 mRNA suggests its potential role in promoting tumor growth, while increased Foxp3 mRNA expression may reflect an immunosuppressive mechanism in CD pathogenesis. These findings provide insights into the molecular and immunological aspects of CRC and CD, warranting further studies for potential therapeutic strategies.PMID:38415552 | DOI:10.31557/APJCP.2024.25.2.647

Source: Asian Pacific Journal of Cancer Prevention - February 28, 2024 Category: Cancer & Oncology Authors: Nastaran Asri Ehsan Nazemalhosseini Mojarad Mohammad Yaghoob Taleghani Hamidreza Houri Mahsa Saeedi Niasar Mostafa Rezaei-Tavirani Somayeh Jahani-Sherafat Amirhossein Shahbazkhani Abdolrahim Nikzamir Mohammad Javad Ehsani Ardakani Mahmood Khodadost Mohamm Source Type: research