Prediction for oxaliplatin ‐induced liver injury using patient‐derived liver organoids

ConclusionsThese results suggested that L-OHP-induced liver injury may be caused by mitochondrial oxidative damage. Furthermore, patient-derived liver organoids may be used to assess susceptibility to L-OHP-induced liver injury in individual patients.

Source: Cancer Medicine - February 24, 2024 Category: Cancer & Oncology Authors: Kumiko Tatsumi, Hiroshi Wada, Shinichiro Hasegawa, Kei Asukai, Shigenori Nagata, Tomoya Ekawa, Takashi Akazawa, Yu Mizote, Shintaro Okumura, Ryosuke Okamura, Masayuki Ohue, Kazutaka Obama, Hideaki Tahara Tags: RESEARCH ARTICLE Source Type: research