Mesenchymal stem cell-derived extracellular vesicles: A novel promising neuroprotective agent for Alzheimer's disease

This study aimed to: outline the diagnostic and delivery roles of MSCs-EVs for AD treatment; summarize the optimal sources and delivery methods of MSCs-EVs; provide a comprehensive review on the neuroprotective mechanisms of MSCs-EVs; explore how to enhance the neuroprotective effects of MSCs-EVs; and discuss the limitations and potential of their translation to the clinic. Therefore, this study may provide a more precise theoretical reference and practical basis for clinical research of MSCs-EVs.PMID:38373595 | DOI:10.1016/j.bcp.2024.116064

Source: Biochemical Pharmacology - February 19, 2024 Category: Drugs & Pharmacology Authors: Jun Chang Zihang Feng Yujiao Li Honglin Lv Shuzhen Liu Yongyin Luo Nan Hao Lan Zhao Jianwei Liu Source Type: research