Sevoflurane causes cognitive impairment by inducing iron deficiency and inhibiting the proliferation of neural precursor cells in infant mice

CONCLUSION: The results from the present study demonstrated that Sev-induced iron deficiency might be a new mechanism of cognitive impairment caused by inhaled anesthetics in infant mice. Iron supplementation before anesthesia is an effective strategy to prevent cognitive impairment caused by Sev in infants.PMID:38334030 | PMC:PMC10853893 | DOI:10.1111/cns.14612

Source: CNS Neuroscience and Therapeutics - February 9, 2024 Category: Neuroscience Authors: Yong Zuo Jinhong Xie Xue Zhang Anand Thirupathi Xiaopeng Liu Di Zhang Jianhua Zhang Zhenhua Shi Source Type: research