Allogeneic Stem Cell Transplantation for Patients with Acute Myeloid Leukemia with Myelodysplasia-Related Features in First Complete Remission As per the International Consensus Classification (ICC) 2022: A Study from the ALWP of the EBMT

Patients (pts) formerly diagnosed as AML with myelodysplasia-related changes are currently recategorized according to their underlying genetic events in three different AML subgroups, namely AML with mutated TP53, AML with myelodysplasia-related gene mutations (MR-GM), and AML with myelodysplasia-related cytogenetic abnormalities (MR-CG) (International Consensus Classification 2022) (Arber AD, Blood 2022). The relevance of this new classification for transplantation (HSCT) outcome is largely unknown.

Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: Arnon Nagler, Myriam Labopin, Jurjen Versluis, Jaime Sanz, Tobias Gedde-Dahl, David Burns, Nicolaas Schaap, H élène Labussière-Wallet, Peter von dem Borne, Gwendolyn Van Gorkom, Nathalie Contentin, Andreas Neubauer, Eva-Maria Wagner-Drouet, Nicolaus Kr Tags: 8 Source Type: research