Impact of Wilms Tumor (WT1) Mutation on Relapse and Overall Survival in Acute Myeloid Leukemia Patients Following Allogenic Stem Cell Transplantation

Wilms tumor mutations (WT)-1 are associated with inferior survival in acute myeloid leukemia (AML); but not considered a high-risk genetic category in the European LeukemiaNet (ELN) guidelines. We compared post-allogeneic stem cell transplant (alloSCT) outcomes of WT1mut AML patients with a known poor prognostic category – TP53mut AML.

Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: Vedavyas Gannamani, Anmol Baranwal, Kimberly J. Langer, Mohamed A. Kharfan-Dabaja, Ernesto Ayala, Vivek Roy, James Foran, Hemant Murthy, Madiha Iqbal, Jeanne Palmer, Lisa Z Sproat, Saurabh Chhabra, Nandita Khera, Mehrdad Hefazi, Abhishek Mangaonkar, Mark Tags: 138 Source Type: research