Multi-omics analyses of choroid plexus carcinoma cell lines reveal potential targetable pathways and alterations

ConclusionMulti-omics analyses revealed that the two choroid plexus carcinoma cell lines sharedTP53 mutations and other common pathway alterations and activation of NOTCH and WNT pathways. Noticeable differences were also observed. These cell lines can serve as valuable models to propose new treatments in these rare but deadly brain tumors.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research