Decreased percentages of plasmacytoid dendritic cells predict survival in critically ill patients

In conclusion, we observed low percentages of DCs in patients admitted to an ICU suffering from sepsis, respiratory failure, and cardiogenic shock, suggesting their depletion as a contributing mechanism for the development of immune paralysis. In our cohort, pDCs were identified as the most robust subset to predict 30-day mortality.PMID:38180532 | DOI:10.1093/jleuko/qiae003

Source: Journal of Leukocyte Biology - January 5, 2024 Category: Hematology Authors: Eva Steinacher Max Lenz Konstantin A Krychtiuk Christian Hengstenberg Kurt Huber Johann Wojta Gottfried Heinz Alexander Niessner Walter S Speidl Lorenz Koller Source Type: research