GDF-10 Induces an Inhibitory Effect on Epithelial-Mesenchymal Transition of Laryngeal Cancer via LPR4

CONCLUSION: Our findings support that GDF-10 can inhibit the proliferation, migration, and invasion, and promote apoptosis of laryngeal carcinoma AMC-HN-8 cells. GDF-10 inhibits the EMT of laryngeal carcinoma through LRP4 and thus inhibits the progression of laryngeal carcinoma.PMID:38163971 | DOI:10.2174/0113816128261029231206035206

Source: Current Pharmaceutical Design - January 2, 2024 Category: Drugs & Pharmacology Authors: Xuan Kan Li Ai Ruidi Guan Jianwei Hao Yanan Sun Wei Xiu Source Type: research