Effects of mirabegron on brown adipose tissue and metabolism in humans: A systematic review and meta-analysis

ConclusionThrough our meta-analysis of 6 papers, we found that mirabegron has the potential to increase human BAT activity, REE, NEFA content, body temperature, HR, blood pressure, and blood insulin content. These effects may lead to reductions in blood glucose levels in obese/overweight and diabetic patients. Additionally, the activation of BAT by mirabegron could represent a novel approach for treating obesity, diabetes, and cardiovascular disease.Trial registration number and dateCRD42023413446, 04/11/2023.
Source: European Journal of Clinical Pharmacology - Category: Drugs & Pharmacology Source Type: research