High-dose chemotherapy with autologous stem-cell transplantation for relapsed metastatic germ cell tumors: The Alberta experience

CONCLUSIONS: We found that HDC-ASCT is an effective salvage therapy in mGCT, consistent with existing literature. Patients appeared to benefit regardless of primary site. Though limited by small sample size, we found a numerical difference in DFS and OS between second- and third-line HDC-ASCT and single vs. tandem ASCT.PMID:38010229 | DOI:10.5489/cuaj.8493

Source: Canadian Urological Association Journal - November 27, 2023 Category: Urology & Nephrology Authors: Hanbo Zhang Nimira S Alimohamed Naveen S Basappa Tina Cheng Michael Chu Nanette Cox-Kennett D Scott Ernst Amelie Fontaine Sunita Ghosh Daniel Y C Heng Richard Littleton Scott North Cindy Railton Irwindeep Sandhu Trevor H Stenson Douglas A Stewart Christop Source Type: research