Kindlin-2 regulates colonic cancer stem-like cells survival and self-renewal via Wnt/ β-catenin mediated pathway

CONCLUSION: Our study delineates the isoform-specific activity of Kindlin-2 in regulating Colonic CSC. Isoform-specific targeting of Kindlin-2 may be a novel strategy to tackle this devastating disease.PMID:38084837 | DOI:10.1016/j.cellsig.2023.110953

Source: Cellular Signalling - December 12, 2023 Category: Cytology Authors: Ravi Prakash Yadav Somesh Baranwal Source Type: research