The causal relationship between ankylosing spondylitis and the risk of ovarian cancer

CONCLUSION: Our Mendelian randomization analysis provides strong evidence supporting a potential causal relationship between AS and ovarian cancer risk, with ankylosing spondylitis clearly associated with an increased risk of ovarian cancer. Tumor necrosis factor receptor superfamily member 21 as a mediator involved in the occurrence and development of these two diseases.PMID:38040544 | DOI:10.1016/j.humimm.2023.110738
Source: Human Immunology - Category: Allergy & Immunology Authors: Source Type: research