Anti-angiogenic Potential of Trans-chalcone in an In Vivo Chick Chorioallantoic Membrane Model: An ATP Antagonist to VEGFR with Predicted Blood-brain Barrier Permeability
CONCLUSION: The present study showed TC to possess anti-angiogenic potential via the inhibition of VEGFR-2. In addition, the study predicted TC to cross BBB as well as a safe alternative for GBM therapy, which needs further investigation.PMID:37936455 | DOI:10.2174/0118715257250417231019102501
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - Category: Cardiology Authors: Anna Senrung Tanya Tripathi Nikita Aggarwal Divya Janjua Arun Chhokar Joni Yadav Apoorva Chaudhary Kulbhushan Thakur Tejveer Singh Alok Chandra Bharti Source Type: research